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Published Research Papers References

The inventor has researched various areas in connection with new drug discovery. Some of the work is published in international, peer-reviewed scientific journals. Here is a list of recent articles.


  1. Acute, subacute, repeated dose toxicity and safety studies of BiosimCovex (COVID-19 Nosode) in animal model
  2. A Randomized, Placebo-controlled Homeopathic Drug-proving of SARS CoV-2 nosode (BiosimCovex) in healthy volunteers
  3. An experimental in vitro study to evaluate the antimalarial activity of select homeopathy preparations
  4. Evaluation of melanogenic and anti-vitiligo activities of homeopathic preparations on murine b16f10 melanoma cells
  5. Biophysical techniques revealed insight of potentized solvent of ethanol-water interface
  6. Preparation and standardisation of Plasmodium falciparum nosode
  7. Evaluating the anticancer effects of high-dilution preparations of carcinogens such as HIV virus, Hepatitis C virus, Ethanol and Cancer tissues in in-vitro models
  8. Preparation of Cancer Nosodes from specific cancer tissues
  9. Therapeutic potential of HIV nosode 30c as evaluated in A549 lung cancer cells
  10. An In-Vitro Assay Estimating Changes in Melanin Content of Melanoma Cells due to Ultra-Dilute, Potentized Preparations
  11. Symptom Similarity versus Disease Similarity: Revisiting the Application of the Law of Similars and Challenging the Symptom-Centric Approach in Homeopathy
  12. Quantitative and Qualitative Pathogenetic Indices for Review of Data Derived from Homeopathic Pathogenetic Trials
  13. The Challenge of Non-Reproducibility of Old Homoeopathic Drugs and the Need for their Standardisation and Re-Proving
  14. A Randomised, Double-Blind Placebo-Controlled, Multi-Centric Clinical Trial of Ultra-Diluted Mycobacterium tuberculosis Nosode (Emtact 30c) in the Management of Recurrent Upper and Lower Respiratory Tract Affections
  15. Safety and Evaluation of the Immune Response of Coronavirus Nosode (BiosimCovex) in Healthy Volunteers: A Preliminary Study Extending the Homeopathic Pathogenetic Trial.
  16. Proposed Standards and Regulatory Mechanisms for New Homeopathic Drug Development.
  17. “Randomized Double-Blind, Placebo-Controlled Feasibility Study, Evaluating the Efficacy of Homeopathic Medicines in the Prevention of COVID-19 in a Quarantined Population”
  18. In-Vitro Evaluation of Antimicrobial Activities of Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Neisseria gonorrhoeae, and Candida albicans Nosodes
  19. Preparation and Standardization of Nosodes Sourced from Klebsiella Pneumoniae, Salmonella Typhi, Neisseria Gonorrhoeae and Candida Albicans Strains
  20. An open-label, exploratory documentation of proving-symptoms of CVN01 (Coronavirus nosode from the clinical sample) in healthy volunteers
  21. “Preparation of Coronavirus nosodes sourced from a clinical sample of SARS-Cov-2 positive patient, inactivated strain, and spike glycoprotein ” International Journal of High Dilutions, Brazil, 2020. Sandeepan MukherjeeGitanjali TaleleAbhay ChowdharyShashikant VaidyaRajesh DeshmukhRakesh RawalRajesh Shah
  22. “Preparation and Standardization of Escherichia coli Nosodes Sourced from Select E. coli Strains”
    Renuka Munshi, Gitanjali Talele. Rajesh Shah, Homeopathy, The Faculty of Homeopathy, 2020, Available from
  23. “The Preparation and standardization of Human papillomavirus (HPV) (Genotype 6) Nosode”, Rajesh Shah, International Journal of High Dilutions, Vol 18 No 3-4 (2019): IJHDR, available from
  24. “Preclinical evaluation of antiarthritic activity of ultra-diluted preparations of Capsaicin alkaloids (CP-10), Tumor necrosis factor-alpha, and Magnesium phosphoricum in wistar rats” Shah Rajesh, Sathaye S., Indian J Res Homoeopathy [serial online] 2017 [cited 2017 Mar 2];11:34-40. Available from:
  25. “Standardization of the potentizing machine and quantification of impact of potentization.” Indian J Res Homoeopathy [serial online] 2016 [cited 2016 Sep 9];10:126-32. Available from:
  26. “A homeopathic nosode, Hepatitis C 30 demonstrates anticancer effect against liver cancer cells in vitro by modulating telomerase and topoisomerase II activities as also by promoting apoptosis via intrinsic mitochondrial pathway”, Khuda Bukhsh AR. Shah Rajesh. Das J. Mondal J. Journal of Integrative Medicine, May 2016, Vol.14, No.3.pp 209-18,
  27. “Preparation, standardization and in vitro safety testing of Mycobacterium nosodes (Emtact- polyvalent nosode)”, Suvarna Joshi, Sandeepan Mukerjee, Shashikant Vaidya, Gitanjali Talele, Abhay Chowdhary, Rajesh Shah. In Homeopathy; Vol. 105, (2), : April 2016.
  28. “A Clinical Evaluation of a Hepatitis C Nosode in the Treatment of Hepatitis C”
    Shah Rajesh. The Journal of Alternative and Complementary Medicine. March 2016, 22(3): 197-203.
  29. “Clinical trial for evaluation of a Human Immunodeficiency Virus nosode in the treatment for Human Immunodeficiency Virus‑ Infected individuals”; Indian Journal of Research in Homoeopathy / Vol. 9 / Issue 1 / Jan-Mar 2015;year=2015;volume=9;issue=1;spage=25;epage=33;aulast=Shah
  30. “HIV Nosode: The Homeopathic Pathogenetic Trial,” by Rajesh Shah, MD, published in Forschende Komplementärmedizin / Research in Complementary Medicine, Germany, June 2015.  Link:
  31. “Scientific method of preparing homoeopathic nosodes” Indian Journal of Research in Homoeopathy [serial online] 2014 [cited 2014 Nov 13];9: 25-33. Available from:
  32. “Effect of Orally Administered Potentized Capsaicin and Dihydrocapsaicin in Humans: A Homeopathic Pathogenetic Trial”, by Rajesh Shah, MD, published in Forschende Komplementärmedizin/ Research in Complementary Medicine, Germany, June 2014.  Link:
  33. “Potentized, oral preparation of capsaicin alkaloids and magnesium phosphoricum in treatment of chronic pain: A clinical trial” by Rajesh Shah, MD, published in American journal “JOURNAL OF PAIN MANAGEMENT”, Nova Publishers, NY, USA, Volume 7, Number 1, 2014 Link:
  34. “Hepatitis C Nosode: The preparation and homeopathic pathogenetic trial” in Homeopathy; Vol. 102, (3), pp 207-214: July 2013.
  35. “Hydroquinone: Homoeopathy pathogenetic trial” in Indian Journal of Research in Homoeopathy; Vol. 7 (2): Apr-Jun 2013.;year=2013;volume=7;issue=2;spage=47;epage=61;aulast=Shah
  36. “Challenge in management of cases earlier treated with immuno-suppressive medicines” (Desafioscolocadosaotratamentohomeopáticopelouso anterior de medicaçãoimunossupressora: Observações da práticaclínica), Revista de Homeopatia, Brazil, Vol. 74, No 4 (2011 )